Abstract: A new procedure is described for locating mineral grains in geological samples prepared for microprobe analysis. This procedure uses a digital image of the entire sample surface to select points of interest. These features of interest must be visible in this external image. Once the sample is mounted on the specimen stage of the microprobe, the digital image is used as a ‘map’ to relocate minerals for analysis. The image can be recorded using either a video camera, fitted with a macro zoom lens, or a flat-bed scanner. A calibration procedure has been developed in which two indexing points are used to calculate the instrument stage coordinates from the pixel coordinates of the digital image. Following this calibration, the stage coordinates of any feature visible in the digital image can be displayed to facilitate rapid relocation. The procedure was evaluated by relocating magnetite grains visible in an optical image of a geological thin section. The repositioning accuracy in relocating 28 magnetite grains distributed over an area of about 20 × 30 mm was found to be 157 ± 102 µm (one standard deviation) from the video camera image and 48 ± 28 µm from a flat bed scanner image. The former image was thought to suffer from some optical distortion. The procedure may be applied to any microprobe instrument fitted with a digital x-y specimen stage. Future applications in relocating features visible in autoradiographs are currently being evaluated.